Prevalence and drug resistance pattern of Listeria monocytogenes among pregnant women in Tigray region, Northern Ethiopia: a cross-sectional study

BMC Res Notes. 2019 Aug 23;12(1):538. doi: 10.1186/s13104-019-4566-8.

Abstract

Objective: The aim of this study was to determine the prevalence and antimicrobial susceptibility test of Listeria monocytogenes among pregnant women in Tigray region, Ethiopia.

Results: The overall prevalence of L. monocytogenes among pregnant women was found to be (8.5%; 12/141). With regard to the socio-demographic characteristics, a high prevalence of L. monocytogenes was observed in the age group of 20-24 years (18.6%; 8/43), rural dwellers (10%; 3/30), secondary school (9.6%; 5/52), and housewives (11.4%;10/88). A high drug resistance rate was observed to penicillin G (66.7%), clindamycin (66.7%), amoxicillin (50%) and vancomycin (50%). However, isolates were relatively sensitive to ciprofloxacin (75%), erythromycin (75%), trimethoprim/sulphamethaxazole (66.7%) and chloramphenicol (60%).

Keywords: Drug resistance; Listeria monocytogenes; Pregnant women; Prevalence; Tigray Region, Ethiopia.

MeSH terms

  • Adolescent
  • Adult
  • Anti-Bacterial Agents / pharmacology*
  • Cross-Sectional Studies
  • Drug Resistance, Microbial / drug effects*
  • Ethiopia / epidemiology
  • Female
  • Humans
  • Listeria monocytogenes / drug effects*
  • Listeria monocytogenes / physiology
  • Listeriosis / drug therapy*
  • Listeriosis / epidemiology
  • Listeriosis / microbiology
  • Microbial Sensitivity Tests / methods
  • Prevalence
  • Rural Population / statistics & numerical data
  • Urban Population / statistics & numerical data
  • Young Adult

Substances

  • Anti-Bacterial Agents