Cutaneous manifestations of angioimmunoblastic T-cell lymphoma

Dermatol Online J. 2019 Jul 15;25(7):13030/qt8nt8r6k4.

Abstract

Angioimmunoblastic T-cell lymphoma (AITL) is a rare form of non-Hodgkin lymphoma often accompanied by autoimmune and paraneoplastic phenomena. Up to 50% of patients with AITL present with skin manifestations. This case series highlights two cases of AITL presenting with unusual cutaneous findings: one with a medium-vessel vasculitis and another with a chronic urticarial eruption. Clinicians should consider AITL in the differential diagnosis of vasculitis or urticaria refractory to standard treatment.

Publication types

  • Case Reports

MeSH terms

  • Fatal Outcome
  • Female
  • Humans
  • Immunoblastic Lymphadenopathy / pathology
  • Lymphoma, T-Cell, Cutaneous / complications*
  • Lymphoma, T-Cell, Cutaneous / pathology
  • Middle Aged
  • Paraneoplastic Syndromes / pathology*
  • Skin / pathology*
  • Skin Neoplasms / complications*
  • Skin Neoplasms / pathology
  • Urticaria / etiology*
  • Urticaria / pathology
  • Vasculitis / etiology*
  • Vasculitis / pathology