Purpose: A clinical case presenting secondary amenorrhea accompanied by an adrenal adenoma and hyperprogesteronemia is described in this study.
Methods: Selective catheterization and sampling of adrenal and ovarian veins were performed.
Results: The source of hyperprogesteronemia was located in the right adrenal gland. A progesterone-producing tumor in the right adrenal gland was diagnosed and removed. Twenty-six days after tumor resection, menstruation occurred.
Conclusions: Progesterone-producing tumors should be considered with the presence of an adrenal mass and hyperprogesteronemia. Combined adrenal and ovarian venous sampling may help to identify the source of progesterone secretion.
Keywords: Amenorrhea; Combined adrenal and ovarian venous sampling; Progesterone-producing tumor.