Abstract
We implemented a guideline for appropriate acid suppressant use in hematology-oncology patients. This intervention resulted in a sustained reduction in proton pump inhibitor (PPI) use without an increase in rates of gastrointestinal bleeding. Practice guidelines are effective in reducing PPI use, which is associated with risk of Clostridioides difficile infection.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Clostridium Infections / epidemiology
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Clostridium Infections / prevention & control*
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Gastrointestinal Hemorrhage / epidemiology
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Gastrointestinal Hemorrhage / prevention & control*
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Hematology / standards
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Hospital Units
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Humans
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Pennsylvania
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Practice Guidelines as Topic*
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Proton Pump Inhibitors / therapeutic use*
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Regression Analysis
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Risk Factors
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Tertiary Care Centers