An Overview of Uncommon Cutaneous Malignancies, Including Skin Appendageal (Adnexal) Tumours and Sarcomas

Clin Oncol (R Coll Radiol). 2019 Nov;31(11):769-778. doi: 10.1016/j.clon.2019.07.019. Epub 2019 Aug 26.

Abstract

A standardised classification of malignant skin appendageal (adnexal) tumours and sarcomas is required for improved patient management and prognosis. This has been hindered by considerable morphological variation both within and between tumour types, the use of many synonyms for the same tumour types and variation in classification between pathologists. This update uses the improved classification in the 2018 WHO classification of skin tumours as the basis to discuss malignant skin appendageal tumours, sarcomas and cutaneous metastases that regularly present to skin cancer clinicians, multidisciplinary skin cancer teams and tumour boards, with current evidence for management, where appropriate.

Keywords: Appendageal; adnexal; cutaneous; pathology; sarcoma; tumour.

Publication types

  • Review

MeSH terms

  • Female
  • Humans
  • Male
  • Neoplasms, Adnexal and Skin Appendage / diagnosis*
  • Neoplasms, Adnexal and Skin Appendage / pathology
  • Sarcoma / diagnosis*
  • Sarcoma / pathology
  • Skin Neoplasms / diagnosis*
  • Skin Neoplasms / pathology