FFRCT and CT perfusion: A review on the evaluation of functional impact of coronary artery stenosis by cardiac CT

Edoardo Conte; Jeroen Sonck; Saima Mushtaq; Carlos Collet; Takuya Mizukami; Emanuele Barbato; Alessandra Tanzilli; Flavia Nicoli; Bernard De Bruyne; Daniele Andreini

doi:10.1016/j.ijcard.2019.08.018

FFR_CT and CT perfusion: A review on the evaluation of functional impact of coronary artery stenosis by cardiac CT

Int J Cardiol. 2020 Feb 1:300:289-296. doi: 10.1016/j.ijcard.2019.08.018. Epub 2019 Aug 9.

Authors

Affiliations

¹ Monzino Cardiology Center, IRCCS, Milan, Italy.
² Cardiovascular Center Aalst, OLV Clinic, Aalst, Belgium; Department of Advanced Biomedical Sciences, University of Naples, Federico II, Naples, Italy.
³ Cardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
⁴ Sapienza University, Policlinico Umberto I, Rome, Italy.
⁵ Cardiovascular Center Aalst, OLV Clinic, Aalst, Belgium; Department of Cardiology, Lausanne University Center Hospital, Lausanne, Switzerland.
⁶ Monzino Cardiology Center, IRCCS, Milan, Italy; Department of Clinical Sciences and Community Health, Cardiovascular Section, University of Milan, Milan, Italy. Electronic address: [email protected].

PMID: 31466886
DOI: 10.1016/j.ijcard.2019.08.018

Abstract

Coronary computed tomography angiography (CCTA) is at the frontline of the diagnostic strategies to detect coronary artery disease (CAD). Anatomical information have proven to be insufficient to detect hemodynamic significant epicardial stenosis. In the present invited review we discuss on FFR_CT and stress CTP, emerging technologies for an accurate and comprehensive evaluation of patients with suspected CAD, offering both anatomical (i.e. luminal and plaque) and functional assessment in one single technique.

Keywords: Cardiac CT; Coronary artery disease; FFR(CT); Myocardial CT perfusion.

Publication types

Review

MeSH terms

Clinical Trials as Topic / methods
Computed Tomography Angiography / methods
Computed Tomography Angiography / standards*
Coronary Angiography / methods
Coronary Angiography / standards*
Coronary Stenosis / diagnostic imaging*
Coronary Stenosis / physiopathology
Fractional Flow Reserve, Myocardial / physiology*
Humans