Prediction and Treatment of Radiation Enteropathy: Can Intestinal Bugs Lead the Way?

Clin Cancer Res. 2019 Nov 1;25(21):6280-6282. doi: 10.1158/1078-0432.CCR-19-2422. Epub 2019 Sep 6.

Abstract

Radiation-induced gastrointestinal toxicity is a significant comorbidity affecting many patients with cancer. Intestinal microbial changes are observed in patients suffering from radiation enteropathy, although a causal relationship with disease activity has yet to be proven. Implementation of bacterial profiling in clinical care could improve recognition and management of this debilitating disease.See related article by Reis Ferreira et al., p. 6487.

Publication types

  • Comment

MeSH terms

  • Humans
  • Intestinal Diseases*
  • Intestines
  • Microbiota*
  • Pilot Projects
  • Radiation Injuries*