Understanding trauma-induced hippocampal subfield volume changes in the context of age and health. Response to Malhi et al

J Affect Disord. 2020 Jan 1:260:24-25. doi: 10.1016/j.jad.2019.08.029. Epub 2019 Aug 18.

Abstract

It is important to integrate findings converging from different perspectives to better contextualize hippocampal subfield changes induced by childhood trauma (CT). Here we integrate Malhi's et al. model on this issue. Understanding the complex neurobiological mechanisms underpinning CT could address the multifaceted nature of resilience to traumatic life experiences that may cause different effects in health and disease.

Keywords: Bipolar disorder; Childhood trauma; Hippocampus; Stress.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Child
  • Health
  • Hippocampus*
  • Humans
  • Magnetic Resonance Imaging*
  • Organ Size