Pulling in new directions: Myosin 2, Piezo, and metabolism

F1000Res. 2019 Aug 22:8:F1000 Faculty Rev-1486. doi: 10.12688/f1000research.18856.1. eCollection 2019.

Abstract

Myosin 2 plays a central role in numerous, fundamental, actin-based biological processes, including cell migration, cell division, and the adhesion of cells to substrates and other cells. Here, we highlight recent studies in which the forces created by actomyosin 2 have been shown to also impact tension-sensitive ion channels and cell metabolism.

Keywords: metabolism; myosin; piezo.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, N.I.H., Intramural
  • Review

MeSH terms

  • Actomyosin / physiology*
  • Cell Adhesion
  • Cell Division
  • Cell Movement
  • Humans
  • Ion Channels / physiology*
  • Myosin Type II / physiology*

Substances

  • Ion Channels
  • Actomyosin
  • Myosin Type II