Pharmacologic stress cardiovascular magnetic resonance in the pediatric population: A review of the literature, proposed protocol, and two examples in patients with Kawasaki disease

Congenit Heart Dis. 2019 Nov;14(6):1166-1175. doi: 10.1111/chd.12840. Epub 2019 Sep 9.

Abstract

Pharmacologic stress cardiovascular magnetic resonance (PSCMR) is a well-established and reliable diagnostic tool for evaluation of coronary artery disease in the adult population. Stress imaging overall and PSCMR in particular is less utilized in the pediatric population with limited reported data. In this review, we highlight the potential use of PSCMR in specific pediatric cohorts with congenital and acquired heart disease, and we review the reported experience. A suggested protocol is presented in addition to two case examples of patients with Kawasaki disease where PSCMR aided decision making.

Keywords: acquired coronary artery disease; congenital heart disease; magnetic resonance imaging; perfusion; pharmacologic stress imaging.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Adult
  • Cardiotonic Agents / administration & dosage*
  • Child
  • Child, Preschool
  • Clinical Protocols
  • Coronary Aneurysm / diagnostic imaging*
  • Coronary Aneurysm / etiology
  • Coronary Aneurysm / physiopathology
  • Coronary Aneurysm / therapy
  • Coronary Artery Disease / diagnostic imaging*
  • Coronary Artery Disease / etiology
  • Coronary Artery Disease / physiopathology
  • Coronary Artery Disease / therapy
  • Disease Progression
  • Female
  • Humans
  • Magnetic Resonance Imaging*
  • Male
  • Mucocutaneous Lymph Node Syndrome / complications*
  • Mucocutaneous Lymph Node Syndrome / diagnosis
  • Myocardial Perfusion Imaging / methods*
  • Predictive Value of Tests
  • Prognosis
  • Reproducibility of Results
  • Vasodilator Agents / administration & dosage*
  • Young Adult

Substances

  • Cardiotonic Agents
  • Vasodilator Agents