ACE inhibitors and ARBs: Managing potassium and renal function

Cleve Clin J Med. 2019 Sep;86(9):601-607. doi: 10.3949/ccjm.86a.18024.

Abstract

Angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs) are used primarily to treat hypertension and are also useful for conditions such as heart failure and chronic kidney disease, independent of their effect on blood pressure. This article reviews the indications for ACE inhibitors and ARBs and offers advice for managing their adverse effects, particularly declining renal function and hyperkalemia.

Publication types

  • Review

MeSH terms

  • Angiotensin Receptor Antagonists / adverse effects*
  • Angiotensin-Converting Enzyme Inhibitors / adverse effects*
  • Creatinine / blood
  • Glomerular Filtration Rate / drug effects*
  • Heart Failure / drug therapy
  • Humans
  • Hyperkalemia / chemically induced*
  • Hypertension / drug therapy
  • Kidney / drug effects
  • Potassium / blood*
  • Renal Insufficiency, Chronic / drug therapy

Substances

  • Angiotensin Receptor Antagonists
  • Angiotensin-Converting Enzyme Inhibitors
  • Creatinine
  • Potassium