Herpes simplex virus-1 as a rare etiology of isolated acute cerebellitis: case report and literature review

J Neurovirol. 2020 Apr;26(2):270-272. doi: 10.1007/s13365-019-00802-6. Epub 2019 Sep 12.

Abstract

Acute cerebellitis is one of the most common cerebellar disorders and occurs due to para-infectious, post-infectious, or post-vaccination cerebellar inflammation. Herpes simplex virus-1 (HSV-1) is known as a common infectious cause of sporadic encephalitis. Cerebellar involvement of HSV-1 is rare and almost always associated with meningoencephalitis. To date, HSV-1 has been identified as the cause of acute isolated cerebellitis in only two patients. Here we report another case of isolated acute cerebellitis caused by HSV-1 in a 20-month-old boy.

Keywords: Cerebellar ataxia; Cerebellitis; Encephalitis; Herpes simplex virus 1, human.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Cerebellar Diseases / virology*
  • Cerebellum / pathology*
  • Encephalitis, Herpes Simplex / pathology*
  • Herpes Simplex / pathology*
  • Herpesvirus 1, Human
  • Humans
  • Infant
  • Male