Risk factors affecting the prognosis of urinary tract infection in Chinese pediatric patients: Single-center experience

Pediatr Int. 2020 Feb;62(2):189-192. doi: 10.1111/ped.14007.

Abstract

Background: Urinary tract infection (UTI) is common in children. The purpose of this retrospective study was to determine the various risk factors that usually affect the prognosis of UTI in children diagnosed with the disease.

Methods: In the present retrospective study, we enrolled all pediatric patients diagnosed with UTI and hospitalized between 1 January 2013 and 31 July 2016 at Nanjing Children's Hospital. We then collected all the relevant patient clinical demographics and characteristics.

Results: The study involved 2,092 pediatric patients diagnosed with UTI. On logistic regression analysis, factors that could affect the prognosis of pediatric UTI were complications, hospitalization, intensive care unit (ICU) admission, type of UTI, urine culture results, blood lymphocytes, urine nitrites (NIT) and antibiotics (unstandardized coefficients, 0.06, <0.001, -0.28, 0.32, <0.001, 0.01, -0.11, 0.01, respectively, all P < 0.001).

Conclusion: Complications, hospitalization, type of UTI, urine culture results, blood lymphocytes, and antibiotics had a significant, positive association with UTI prognosis. Meanwhile, ICU admission and urine NIT had a negative association with prognosis.

Keywords: pediatrics; risk factor; urinary tract infection.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Child, Preschool
  • China / epidemiology
  • Female
  • Hospitalization
  • Hospitals, Pediatric
  • Humans
  • Intensive Care Units
  • Male
  • Prognosis
  • Retrospective Studies
  • Risk Factors
  • Urinalysis
  • Urinary Tract Infections / diagnosis*
  • Urinary Tract Infections / drug therapy
  • Urinary Tract Infections / epidemiology

Substances

  • Anti-Bacterial Agents