Hemispherotomy can cause post-operative strabismus

Brain Dev. 2020 Jan;42(1):41-47. doi: 10.1016/j.braindev.2019.08.011. Epub 2019 Sep 11.

Abstract

Background: Hemispherotomy, which involves disconnecting hemispherical fibers, is a treatment option for medically intractable epilepsy. As various neurological disorders can cause strabismus, we hypothesized that hemispherotomy can cause post-operative strabismus in patients with medically intractable epilepsy.

Methods: Nineteen patients underwent the Hirschberg test before and after hemispherical disconnection surgery. Among the 19 patients, 16 patients (six females and 10 males; mean age, 12.2 years; range, 0.17-43 years) who underwent hemispherotomy were included in this study.

Results: The difference in the angle between the left and right eyes was significantly widened (p = 0.025). Nine (56%) of 16 patients exhibited post-operative chronic strabismus as evaluated with the Hirschberg test. Intermittent strabismus was noticed by family members or caregivers in 10 (63%) of 16 patients. Patients older than 12 years did not show post-operative strabismus as evaluated by the Hirschberg test.

Conclusion: Hemispherotomy can cause or worsen post-operative strabismus in pediatric patients.

Keywords: Complication; Hemispherotomy; Hirschberg test; Plasticity; Strabismus.

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Drug Resistant Epilepsy / surgery*
  • Female
  • Hemispherectomy / adverse effects*
  • Humans
  • Infant
  • Male
  • Postoperative Complications / etiology*
  • Strabismus / etiology*
  • Young Adult