[Loss of human ICOSLG results in combined immunodeficiency]

Med Sci (Paris). 2019 Aug-Sep;35(8-9):625-628. doi: 10.1051/medsci/2019126. Epub 2019 Sep 18.
[Article in French]
No abstract available

Publication types

  • Case Reports
  • News

MeSH terms

  • Adult
  • Amino Acid Substitution
  • Antigen Presentation
  • Chemotaxis, Leukocyte
  • Golgi Apparatus / chemistry
  • Humans
  • Immunogenicity, Vaccine
  • Inducible T-Cell Co-Stimulator Ligand / chemistry
  • Inducible T-Cell Co-Stimulator Ligand / deficiency*
  • Inducible T-Cell Co-Stimulator Ligand / genetics
  • Inducible T-Cell Co-Stimulator Ligand / immunology
  • Inducible T-Cell Co-Stimulator Protein / immunology
  • Infections / etiology
  • Lymphocyte Activation
  • Male
  • Mutation, Missense
  • Phenotype
  • Protein Transport
  • Recurrence
  • Severe Combined Immunodeficiency / genetics*
  • Severe Combined Immunodeficiency / immunology
  • T-Lymphocytes / immunology

Substances

  • ICOS protein, human
  • ICOSLG protein, human
  • Inducible T-Cell Co-Stimulator Ligand
  • Inducible T-Cell Co-Stimulator Protein