Emergomyces: The global rise of new dimorphic fungal pathogens

Ilan S Schwartz; Nelesh P Govender; Lynne Sigler; Yanping Jiang; Tsidiso G Maphanga; Barbra Toplis; Alfred Botha; Karolina Dukik; J Claire Hoving; Jose F Muñoz; Sybren de Hoog; Christina A Cuomo; Robert Colebunders; Chris Kenyon

doi:10.1371/journal.ppat.1007977

Emergomyces: The global rise of new dimorphic fungal pathogens

PLoS Pathog. 2019 Sep 19;15(9):e1007977. doi: 10.1371/journal.ppat.1007977. eCollection 2019 Sep.

Authors

Ilan S Schwartz¹, Nelesh P Govender^{2

3}, Lynne Sigler⁴, Yanping Jiang^{5

6}, Tsidiso G Maphanga^{2

7}, Barbra Toplis⁸, Alfred Botha⁸, Karolina Dukik⁵, J Claire Hoving⁹, Jose F Muñoz¹⁰, Sybren de Hoog^{5

11}, Christina A Cuomo¹⁰, Robert Colebunders¹², Chris Kenyon^{13

14}

Affiliations

¹ Division of Infectious Diseases, Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
² National Institute for Communicable Diseases, a Division of the National Health Laboratory Service, Johannesburg, Gauteng, South Africa.
³ Department of Clinical Microbiology and Infectious Diseases, University of the Witwatersrand, Johannesburg, Gauteng, South Africa.
⁴ Department of Biological Sciences, Faculty of Sciences, University of Alberta, Edmonton, Alberta, Canada.
⁵ Westerdijk Fungal Biodiversity Institute, Utrecht, the Netherlands.
⁶ Department of Dermatology, The Affiliated Hospital, Guizhou Medical University, Guiyang, China.
⁷ University of the Free State, Bloemfontein, Free State, South Africa.
⁸ Department of Microbiology, Stellenbosch University, Stellenbosch, Western Cape, South Africa.
⁹ Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, Western Cape, South Africa.
¹⁰ Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.
¹¹ Center of Expertise in Mycology of RadboudUMC/ Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.
¹² Global Health Institute, University of Antwerp, Antwerp, Belgium.
¹³ Clinical Sciences Unit, Institute of Tropical Medicine, Antwerp, Belgium.
¹⁴ Department of Medicine, University of Cape Town, Cape Town, Western Cape, South Africa.

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Biological Evolution
Chrysosporium / genetics
Chrysosporium / metabolism*
Chrysosporium / pathogenicity*
Fungi / genetics
Fungi / pathogenicity*
Humans
Mycoses / metabolism
Mycoses / pathology

Grants and funding

This research was funded by the Fonds Wetenschappelijk Onderzoek – Vlaanderen (G.0514.14N). ISS received salary support from the Association of Medical Microbiology and Infectious Disease Canada–Astellas post-residency fellowship (2014), a Marie Curie Actions International Research Staff Exchange Scheme (2015), the R. Samuel McLaughlin – Manitoba Medical Services Foundation and University of Manitoba Dean's Fellowship Fund (2015/2016), a Detweiler Travelling Fellowship from the Royal College of Physicians and Surgeons of Canada (2017-2018), and the University of Alberta Faculty of Medicine and Dentistry, Department of Medicine. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.