Successful treatment of KPC-MDR septic shock with ceftazidime-avibactam in a pediatric critically ill patient

Maria Vargas; Antonio Riccardo Buonomo; Pasquale Buonanno; Carmine Iacovazzo; Giuseppe Servillo

doi:10.1016/j.idcr.2019.e00634

Successful treatment of KPC-MDR septic shock with ceftazidime-avibactam in a pediatric critically ill patient

IDCases. 2019 Sep 5:18:e00634. doi: 10.1016/j.idcr.2019.e00634. eCollection 2019.

Authors

Maria Vargas¹, Antonio Riccardo Buonomo², Pasquale Buonanno¹, Carmine Iacovazzo¹, Giuseppe Servillo¹

Affiliations

¹ Department of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University, Naples, Italy.
² Department of Clinical Medicine and Surgery - Section of Infectious Diseases, University of Naples Federico II, Naples, Italy.

Abstract

Ceftazidime-avibactam is a combination agent consisting of the β-lactamase inhibitor avibactam and the broad-spectrum cephalosporin ceftazidime. There are no published case reports or studies evaluating the use of CAZ-AVI in pediatric critically ill patients. We report a case of a successful treatment of septic shock due to Klebsiella pneumonie (KP) in a 14-years-old boy (body weight 50 kg) admitted in intensive care unit (ICU).

Keywords: Ceftazidime-avibactam; Pediatric critically ill patient; Septic shock.

Publication types

Case Reports