Effect of intraoperative radiotherapy for early breast cancer on 10-year recurrence rates and overall survival

Breast J. 2020 Mar;26(3):427-432. doi: 10.1111/tbj.13502. Epub 2019 Sep 20.

Abstract

The aim of this study was to evaluate 10-year local control and overall survival of IORT for early breast cancer treatment. We analyzed 68 patients submitted to breast conservative surgery and IORT, in the accelerator room of the Radiotherapy Service in South Brazil. In the long-term follow-up, we had 17.6% of patients with ipsilateral breast cancer recurrence, 2.9% with regional recurrence, 2.9% with contralateral breast recurrence, and 5.9% with distant metastasis. The 10-year overall survival was 82.8%. Our data show high local recurrence rates, however, good overall survival in early breast cancer patients treated with breast-conserving surgery and intraoperative radiotherapy with electron beams in the long-term follow-up.

Keywords: breast cancer; conserving surgery; intraoperative radiotherapy.

MeSH terms

  • Brazil
  • Breast Neoplasms* / radiotherapy
  • Breast Neoplasms* / surgery
  • Female
  • Humans
  • Intraoperative Care
  • Mastectomy
  • Mastectomy, Segmental
  • Neoplasm Recurrence, Local
  • Radiotherapy, Adjuvant