Personal or family history of metabolic traits predispose to higher hepatotoxic effects of alcohol

J Family Med Prim Care. 2019 Aug 28;8(8):2558-2560. doi: 10.4103/jfmpc.jfmpc_439_19. eCollection 2019 Aug.

Abstract

World Health Organization Global Status 2018 Report on alcohol and health states that global total alcohol per capita consumption has drastically risen from 2005 to 2016. Presence of inherited metabolic traits (MTs) such as diabetes, hypertension, and obesity predisposes to early and more severe liver damage, even with smaller quantity and shorter duration of exposure to alcohol. This editorial highlights the need for screening of individuals with either addiction of alcohol or alcoholic liver disease for personal and family history of diabetes, hypertension, obesity, and other MTs for risk stratification and specific interventions. Health education and awareness regarding deleterious effects of alcohol among those who have a personal or family history of MTs should be ensured.

Keywords: Alcohol; alcoholic liver disease; hepatotoxicity; metabolic traits; nonalcoholic fatty liver disease.

Publication types

  • Editorial