Mirror Syndrome with Severe Postpartum Presentation following Stillbirth and Shoulder Dystocia

Fetal Pediatr Pathol. 2020 Oct;39(5):441-445. doi: 10.1080/15513815.2019.1658246. Epub 2019 Sep 27.

Abstract

Background: Mirror syndrome (MS) is a pregnancy-related condition characterized by fetal, placental and maternal edema. Methods: We report a case of MS with severe postpartum presentation following stillbirth, shoulder dystocia, McRoberts maneuver, anterior shoulder disimpaction and manual posterior shoulder delivery together with serum soluble fms-like tyrosine kinase 1 (sFlt-1)/placental growth factor (PlGF) ratio results. Results: A 33-year-old patient G3P0A2 at 34 weeks gestation was referred with fetal Ebstein anomaly and fetal hydrops. At 36 weeks of gestation, examination revealed fetal demise with placental hydrops. Delivery of a stillborn child was complicated by shoulder dystocia. Twelve hours postpartum patient developed massive edema and acute kidney injury. Five days postpartum serum creatinine level (CrL) peaked and the sFlt-1/PlGF ratio was elevated. Twelve days after delivery CrL normalized and edema resolved. Conclusions: Shoulder dystocia may increase the severity of postpartum MS. The sFlt-1/PlGF ratio may be useful for MS management.

Keywords: Acute kidney injury; Ebstein anomaly; hydrops fetalis; shoulder dystocia.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Biomarkers
  • Female
  • Gestational Age
  • Humans
  • Placenta Growth Factor
  • Postpartum Period
  • Pre-Eclampsia*
  • Pregnancy
  • Shoulder Dystocia*
  • Stillbirth*

Substances

  • Biomarkers
  • Placenta Growth Factor