Giant cell reparative granuloma (GCRG) is a type of non-neoplastic lesion that can be rarely found in clinical practices. Due to the lack of specificity in symptoms, signs and auxiliary examinations, it is likely to be misdiagnosed, and thereby affecting the treatment and prognosis. In July 2018, a GCRG patient who was described with "4 years of hearing loss in the left ear, accompanied by 2 months of preauricular swelling" as the first symptom was admitted in our hospital. Both the HRCT and MRI scans for the temporal bone suggested the presence of tumor at the left lateral skull base, but the nature still needed further examination. Intraoperatively, the tumor was completely removed and repaired locally. Pathological examination confirmed the symptoms as GCRG. Immunohistochemistry showed the expression of CD68 and CD163 in the tumor cells. Postoperatively, the patient recovered well without complications, and had the stitches removed before being discharged on schedule.
巨细胞修复性肉芽肿是一种临床上少见的非肿瘤性病变。因其症状、体征及辅助检查缺乏特异性，容易导致误诊，影响患者的治疗和预后。2018年7月中南大学湘雅医院收治了1例以“左耳听力下降4年伴耳前肿胀2个月”为首发症状的巨细胞修复性肉芽肿患者，颞骨高分辨率CT及MRI均提示左侧颅底肿瘤性质待查，术中完整切除肿瘤并局部修复，病理证实为巨细胞修复性肉芽肿，免疫组织化学示肿瘤细胞表达CD68和CD163。术后患者恢复良好，无并发症，按期拆线出院。.