Tailoring a rapid autopsy protocol to explore cancer evolution: a patient collaboration

N Z Med J. 2019 Oct 4;132(1503):83-92.

Abstract

Genomic analysis of tissues from rapid autopsy programmes has transformed our understanding of cancer. However, these programmes are not yet established in New Zealand. Our neuroendocrine tumour research group, NETwork!, received a request from a patient wishing to donate tumour tissues post-mortem. This viewpoint article summarises the ethical, logistical and social process undertaken to accept this patient's generous donation, and highlights the scientific and educational value of such a gift.

MeSH terms

  • Clinical Protocols
  • Databases, Genetic
  • Genetic Heterogeneity
  • Genetic Research*
  • Humans
  • Neoplasms / genetics*
  • Neoplasms / therapy
  • New Zealand
  • Patient Participation* / legislation & jurisprudence
  • Patient Participation* / methods
  • Pharmacogenomic Variants*
  • Specimen Handling* / ethics
  • Specimen Handling* / methods
  • Tissue Banks* / ethics
  • Tissue Banks* / legislation & jurisprudence
  • Tissue Banks* / organization & administration