Is Centralization Needed for Patients Undergoing Distal Pancreatectomy?: A Nationwide Study of 3314 Patients

Pancreas. 2019 Oct;48(9):1188-1194. doi: 10.1097/MPA.0000000000001410.

Abstract

Objective: The centralization of complex surgical procedures is associated with better postoperative outcomes. However, little is known about the impact of hospital volume on the outcome after distal pancreatectomy.

Methods: Using the French national hospital discharge database, we identified all patients having undergone distal pancreatectomy in France between 2012 and 2015. A spline model was applied to determine the caseload cut-off in annual distal pancreatectomy that influenced 90-day postoperative mortality.

Results: A total of 3314 patients were identified. Use of a spline model did not reveal a cut-off in the annual distal pancreatectomy caseload. By taking the median number of distal pancreatectomy (n = 5) and the third quartile (n = 15), we stratified centers into low, intermediate, and high hospital volume groups. The overall postoperative mortality rate was 3.0% and did not differ significantly between these groups. In a multivariable analysis, age, Charlson comorbidity score, septic complications, hemorrhage, shock, and reoperation were independently associated with a greater overall risk of death. However, hospital volume had no impact on mortality after distal pancreatectomy (odds ratio, 0.954; 95% confidence interval, 0.552-1.651, P = 0.867).

Conclusions: Hospital volume does not seem to influence mortality after distal pancreatectomy in France, and centralization may not necessarily improve outcomes.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Databases, Factual / statistics & numerical data*
  • Female
  • France
  • Hospitals, High-Volume / statistics & numerical data
  • Hospitals, Low-Volume / statistics & numerical data
  • Humans
  • Length of Stay / statistics & numerical data*
  • Male
  • Middle Aged
  • Outcome Assessment, Health Care / methods
  • Outcome Assessment, Health Care / statistics & numerical data
  • Pancreatectomy / methods*
  • Pancreatic Neoplasms / surgery*
  • Patient Discharge / statistics & numerical data*
  • Postoperative Complications / diagnosis
  • Postoperative Complications / mortality
  • Survival Rate