Aptamer-guided upconversion nanoplatform for targeted drug delivery and near-infrared light-triggered photodynamic therapy

J Biomater Appl. 2020 Jan;34(6):875-888. doi: 10.1177/0885328219882152. Epub 2019 Oct 17.

Authors

Hui-Chao Lin¹, Wen-Tian Li², Thushara W Madanayake³, Can Tao¹, Qiang Niu¹, Si-Qi Yan¹, Bao-An Gao², Zhao Ping¹

Affiliations

¹ School of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University, Guangzhou, PR China.
² First Clinical Medical College of Three Gorges University, Yichang Central People's Hospital, Yichang City, Hubei Province, PR China.
³ College of Pharmacy, University of Arizona, Tucson, AZ, USA.

PMID: 31623518
DOI: 10.1177/0885328219882152

No abstract available

Keywords: Upconversion nanoparticles; aptamer; photodynamic therapy; protoporphyrin IX.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antineoplastic Agents / chemistry*
Antineoplastic Agents / pharmacology
Aptamers, Nucleotide / chemistry*
Biocompatible Materials / chemistry
Biocompatible Materials / metabolism
Cell Membrane Permeability
Cell Movement
Delayed-Action Preparations / chemistry
Drug Liberation
Fluorescent Dyes / chemistry
Fluorides / chemistry*
HeLa Cells
Humans
Infrared Rays
Nanocapsules / chemistry*
Oligodeoxyribonucleotides / chemistry*
Pharmaceutical Preparations
Photochemotherapy
Photosensitizing Agents / chemistry*
Photosensitizing Agents / pharmacology
Polyethylene Glycols / chemistry
Protoporphyrins / chemistry*
Protoporphyrins / pharmacology
Reactive Oxygen Species / chemistry
Yttrium / chemistry*

Substances

AGRO 100
Antineoplastic Agents
Aptamers, Nucleotide
Biocompatible Materials
Delayed-Action Preparations
Fluorescent Dyes
Nanocapsules
Oligodeoxyribonucleotides
Pharmaceutical Preparations
Photosensitizing Agents
Protoporphyrins
Reactive Oxygen Species
sodium yttriumtetrafluoride
Polyethylene Glycols
Yttrium
protoporphyrin IX
Fluorides