Successful treatment of marrow failure after CARTs for myeloma by the infusion of cryopreserved stem cells

Lingzhi Yan; Jingjing Shang; Xiaolan Shi; Huizhu Kang; Wei Liu; Nan Xu; Yong Liu; Guanghua Chen; Liqing Kang; Feiran Gong; Fang Tang; Lei Yu; Depei Wu; Chengcheng Fu

doi:10.1002/ajh.25664

Successful treatment of marrow failure after CARTs for myeloma by the infusion of cryopreserved stem cells

Am J Hematol. 2020 Jan;95(1):E20-E23. doi: 10.1002/ajh.25664. Epub 2019 Nov 9.

Authors

Lingzhi Yan^{1

2}, Jingjing Shang^{1

2}, Xiaolan Shi^{1

2}, Huizhu Kang^{1

2}, Wei Liu¹, Nan Xu^{3

4}, Yong Liu^{1

2}, Guanghua Chen^{1

2}, Liqing Kang^{3

4}, Feiran Gong^{1

2}, Fang Tang^{1

2}, Lei Yu^{3

4}, Depei Wu^{1

2}, Chengcheng Fu^{1

2}

Affiliations

¹ The First Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, National Clinical Research Center for Hematologic Diseases, Suzhou, China.
² Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China.
³ Shanghai Unicar-Therapy Bio-medicine Technology Co., Ltd, Shanghai, China.
⁴ Institute of Biomedical Engineering and Technology, Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai, China.

No abstract available

Publication types

Case Reports
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Antigens, CD19 / therapeutic use
Bone Marrow Failure Disorders / etiology*
Bone Marrow Failure Disorders / therapy
Cryopreservation
Hematopoietic Stem Cell Transplantation / methods*
Humans
Immunotherapy, Adoptive / adverse effects*
Male
Multiple Myeloma / therapy*
Pancytopenia / etiology
Receptors, Chimeric Antigen
Stem Cells / cytology
Transplantation, Autologous
Treatment Outcome

Substances

Antigens, CD19
CD19 molecule, human
Receptors, Chimeric Antigen

Publication types

MeSH terms

Substances

Grants and funding