Genome sequence of a pathogenic Corynebacterium ulcerans strain isolated from a wild boar with necrotizing lymphadenitis

BMC Res Notes. 2019 Oct 25;12(1):692. doi: 10.1186/s13104-019-4704-3.

Abstract

Objectives: Corynebacterium ulcerans can colonize a wide variety of animals and also humans are infected, typically by zoonotic transmission. Symptoms range from skin ulcers or systemic infections to diphtheria-like illness. In contrast, Corynebacterium pseudotuberculosis is widely distributed among herds of sheep, goats and other farm animals, where it causes high economic losses due to caseous lymphadenitis. Here we describe the genome sequence of an atypical C. ulcerans strain isolated from a wild boar with necrotizing lymphadenitis. This strain has similarities to C. pseudotuberculosis.

Data description: Genome sequence data of C. ulcerans isolate W25 were generated, analyzed and taxonomical relationship to other Corynebacterium species as well as growth properties of the isolate were characterized. The genome of C. ulcerans W25 comprises 2,550,924 bp with a G+C content of 54.41% and a total of 2376 genes.

Keywords: Emerging pathogen; Genomics; Toxigenic corynebacteria; Zoonotic transmission.

MeSH terms

  • Animals
  • Corynebacterium / classification
  • Corynebacterium / genetics*
  • Corynebacterium / isolation & purification
  • Corynebacterium Infections / microbiology
  • Corynebacterium Infections / veterinary*
  • Corynebacterium pseudotuberculosis / genetics
  • Corynebacterium pseudotuberculosis / physiology
  • Exome Sequencing / methods
  • Genome, Bacterial / genetics*
  • Histiocytic Necrotizing Lymphadenitis / diagnosis*
  • Histiocytic Necrotizing Lymphadenitis / microbiology
  • Humans
  • Phylogeny
  • Sus scrofa
  • Swine
  • Swine Diseases / diagnosis*
  • Swine Diseases / microbiology