Nocturnal systolic blood pressure pattern of type 2 diabetic hypertensive men with erectile dysfunction: a cross sectional study from Northern Sri Lanka

BMC Res Notes. 2019 Oct 25;12(1):696. doi: 10.1186/s13104-019-4740-z.

Abstract

Objective: This small scale cross-sectional study was done to identify the common systolic blood pressure pattern (dipping or non-dipping) among type 2 diabetic men with coexisting hypertension and erectile dysfunction(ED). A recent study in the same setting showed that prevalence of ED was high among diabetic men and co-existing hypertension was identified as an independent risk factor. There was a postulation about an association between ED and non-dipping nocturnal blood pressure pattern. So ambulatory blood pressure measurements (ABPM) was obtained for participants to test this prediction. Data was analysed using SPSS 25 Version.

Results: Among 29 participants who underwent ABPM, 21 showed non-dipping pattern of nocturnal systolic blood pressure (72.4%; CI 54.3-86.3). Mean SBP of participants was 125.55 +_14.1 and Mean DBP was 81.5 + _12.82. There was no statistical difference observed in mean SBP and DBP between patients with dipping nocturnal SBP and non-dipping pattern (P > 0.05). Variability of SBP was high among the participants (Mean SD-11.96 +/_2.74) and DBP also showed relatively high variability (SD-9.28 +/_2.9). Mean dipping percentage of the SBP during sleep was 5.54 +/_6.66. A significant difference in heart rate (HR) between patients with non-dipping and dipping pattern was noted (P-0.034).

Keywords: Diabetes; Erectile dysfunction; Nocturnal blood pressure pattern; Northern Sri Lanka.

MeSH terms

  • Blood Pressure / physiology*
  • Blood Pressure Monitoring, Ambulatory / methods
  • Blood Pressure Monitoring, Ambulatory / statistics & numerical data
  • Circadian Rhythm / physiology*
  • Comorbidity
  • Cross-Sectional Studies
  • Diabetes Mellitus, Type 2 / epidemiology
  • Diabetes Mellitus, Type 2 / physiopathology*
  • Erectile Dysfunction / epidemiology
  • Erectile Dysfunction / physiopathology*
  • Heart Rate / physiology
  • Humans
  • Hypertension / epidemiology
  • Hypertension / physiopathology*
  • Male
  • Middle Aged
  • Prevalence
  • Risk Factors
  • Sri Lanka / epidemiology
  • Time Factors