Objective: To investigate the association between daily sedentary time and frailty among people aged 50 years and over. Methods: Cross-sectional data was collected from the first wave of World Health Organization Study on global AGEing and adult health in China. A two-level (individual level and community level) logistic model was performed to identify the association between daily sedentary time and frailty. The dose-response relationship between them was analyzed by restrictive cubic spline curve. Results: A total of 13 175 individuals aged 50 years and over were included for analysis. A positive association between daily sedentary time and frailty was noticed, both in urban (OR=1.22, 95%CI: 1.17-1.27) or rural areas (OR=1.11, 95%CI: 1.05-1.18) under study. The dose-response curve showed that daily sedentary time and frailty might present an approximate linear relationship. Conclusion: Results from this study showed significant association exsited between daily sedentary time and frailty, approximately with a linear dose-response relationship.
目的： 分析≥50岁人群中每日静坐时间与衰弱发生的关系。 方法： 利用WHO全球老龄化与成人健康研究中国项目第一轮基线调查，采用两水平（个体层面和社区层面）logistic回归模型按城乡进行分层分析每日静坐时间与衰弱的关系，并采用限制性立方样条曲线分析两者之间的剂量-反应关系。 结果： 共纳入13 175名≥50岁中老年人进行分析。城市（OR=1.22，95%CI：1.17~1.27）及农村（OR=1.11，95%CI：1.05~1.18）地区人群每日静坐时间与衰弱发生均显著相关。限制性立方样条曲线显示，每日静坐时间与衰弱发生存在近似线性剂量-反应关系。 结论： 每日静坐时间与衰弱发生显著相关，并呈近似线性关系。.
Keywords: Frailty; Sedentary time.