The novel HLA-DQB1*06:358 allele, identified by Next-Generation Sequencing in a Saudi individual

HLA. 2020 Feb;95(2):157-158. doi: 10.1111/tan.13737. Epub 2019 Nov 11.

Authors

Hanan Alanazi¹, Afnan Alqasem¹, Faisal Aloufi¹, Hannah L Macpherson², Ali H Hajeer¹

Affiliations

¹ HLA Typing Lab, Department of Pathology and Laboratory Medicine, KSAU-HS, MNGHA, Riyadh, Saudi Arabia.
² Anthony Nolan Research Institute, Royal Free Hospital, London, UK.

PMID: 31664784
DOI: 10.1111/tan.13737

Abstract

HLA-DQB1*06:358 differs from HLA-DQB1*06:09:01:01 by two single nucleotide substitutions: 2949 C>T and 3001 A>T.

Keywords: HLA-DQB1; Saudi Arabia; genomic sequence; new allele.

© 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

MeSH terms

Alleles
HLA-DQ beta-Chains / genetics
High-Throughput Nucleotide Sequencing*
Humans
Saudi Arabia

Substances

HLA-DQ beta-Chains
HLA-DQB1 antigen