Analysis of the impact of diagnostic virology tests on the use of antibiotics in paediatric inpatients with community-acquired pneumonia

Enferm Infecc Microbiol Clin (Engl Ed). 2020 May;38(5):230-233. doi: 10.1016/j.eimc.2019.08.008. Epub 2019 Oct 24.
[Article in English, Spanish]

Abstract

Introduction: Viruses are one of the most common causes of community-acquired pneumonia (CAP) in children. Early identification of respiratory viruses could result in a decrease in the use of antibiotics.

Methods: Observational, retrospective study from January 2014 to June 2018, that included paediatric patients admitted with a diagnosis of CAP in a tertiary hospital, in which antigenic tests and/or viral PCR on a respiratory sample was performed.

Results: A total of 105 CAP episodes were included, with identification of a respiratory virus in 93 (88.6%) cases. Patients with respiratory syncytial virus (RSV) detection had a lower onset of empirical antibiotic therapy (35.1% vs. 55.9%, P-value=.042). In addition, cases with RSV or influenza identification required shorter duration of antibiotic therapy (receiving 45.6% ≥2 days vs. 68.8% of those not identified, P=.017).

Conclusion: The use of respiratory virus diagnostic techniques in our setting can optimise antibiotic use in children admitted with CAP.

Keywords: Antimicrobial stewardship; Children; Neumonía; Niños; Optimización de consumo de antibióticos; Paediatrics; Pediatría; Pneumonia; Respiratory virus testing; Test de virus respiratorios.

Publication types

  • Observational Study

MeSH terms

  • Anti-Bacterial Agents / administration & dosage*
  • Child
  • Community-Acquired Infections* / drug therapy
  • Community-Acquired Infections* / virology
  • Humans
  • Inpatients
  • Pneumonia, Viral* / diagnosis
  • Retrospective Studies

Substances

  • Anti-Bacterial Agents