Platelet function defects in patients with Gaucher disease on long term ERT- implications for evaluation at bleeding challenges

Blood Cells Mol Dis. 2020 Feb:80:102371. doi: 10.1016/j.bcmd.2019.102371. Epub 2019 Oct 18.

Authors

Veroniki Komninaka¹, Konstantina Repa¹, Theodoros Marinakis², Abraham Pouliakis³, Theodora Koutsouri⁴, Dimitrios Tsokanas², Pagona Flevary¹, Ersi Voskaridou¹, Marianna Politou⁵

Affiliations

¹ Thalassaemia Centre, Laikon Hospital, Athens, Greece.
² Department of Haematology, G.Gennimatas Hospital, Athens, Greece.
³ 2nd Department of Pathology, Attikon Hospital, National and Kapodistrian University of Athens, Greece.
⁴ Hematology Laboratory, Blood Bank, Aretaieion Hospital, University of Athens, Greece.
⁵ Hematology Laboratory, Blood Bank, Aretaieion Hospital, University of Athens, Greece. Electronic address: [email protected].

PMID: 31670186
DOI: 10.1016/j.bcmd.2019.102371

No abstract available

Keywords: Gaucher disease; Hemostasis.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Aged
Biomarkers
Blood Cell Count
Blood Platelets / metabolism*
Enzyme Replacement Therapy / adverse effects
Female
Gaucher Disease / blood*
Gaucher Disease / complications
Gaucher Disease / drug therapy
Gaucher Disease / etiology
Glucosylceramidase / therapeutic use
Hemorrhage / diagnosis
Hemorrhage / etiology
Humans
Male
Middle Aged
Platelet Function Tests
Young Adult

Substances

Biomarkers
Glucosylceramidase