Pharmacophore modeling coupled with scaffold hopping to identify novel and potent ribosomal S6 kinase (RSK2) protein antagonists as anti-cancer agents
J Biomol Struct Dyn
.
2020 Oct;38(16):4947-4955.
doi: 10.1080/07391102.2019.1689172.
Epub 2019 Nov 12.
Authors
Praveen Kumar Guttula
1
,
Kirti Agrawal
1
,
Pradeep Natarajan
1
,
Mukesh Kumar Gupta
1
Affiliation
1
Gene Manipulation Laboratory, Department of Biotechnology and Medical Engineering, National Institute of Technology Rourkela, Odisha, India.
PMID:
31684835
DOI:
10.1080/07391102.2019.1689172
Abstract
Communicated by Ramaswamy H. Sarma.
Publication types
Letter
MeSH terms
Antineoplastic Agents* / pharmacology
Ribosomal Protein S6 Kinases, 90-kDa*
Ribosomal Proteins
Substances
Antineoplastic Agents
Ribosomal Proteins
Ribosomal Protein S6 Kinases, 90-kDa