Rate of growth-A novel surrogate marker for high-risk cutaneous squamous cell carcinoma? A case report and review of the literature

Dermatol Ther. 2020 Jan;33(1):e13156. doi: 10.1111/dth.13156. Epub 2019 Nov 29.

Abstract

Cutaneous squamous cell carcinoma (cSCC) is one of the most common nonmelanoma skin cancer worldwilde, with a more invasive growth pattern and higher potential to metastatize than basal cell carcinoma. Although several risk factors have been linked to a high metastatic potential of cSCC, no widely accepted classification system for this common subtype of cancer exists. Herein we report an emblematic case of rapidly growing and metastatic cSCC and discuss the rate of growth of the tumour (ROG) as novel prognostic high risk surrogate marker.

Keywords: lymphoma-associated skin cancer; non-melanoma-skin-cancer; squamous cell carcinoma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Biomarkers, Tumor
  • Carcinoma, Squamous Cell / pathology*
  • Humans
  • Male
  • Neoplasm Metastasis
  • Prognosis
  • Risk Factors
  • Skin Neoplasms / pathology*

Substances

  • Biomarkers, Tumor