Erythema papulatum centrifugum and new diagnostic criteria

Australas J Dermatol. 2020 Feb;61(1):e87-e90. doi: 10.1111/ajd.13146. Epub 2019 Nov 6.

Abstract

Erythema papulatum centrifugum (EPC), also known as erythema papulosa semicircularis recidivans (EPSR), is distinct from eczema and other well-described figurate erythemas characterised by annular erythematous lesions. We report 7 cases of EPC and propose new diagnostic criteria including the following: (i) EPC is characterised by single or multiple recurrent expanding annular or semi annular erythema with central regression, surrounded by tiny red papules; (ii) the lesions regularly relapse and resolve; (iii) the histopathologic feature shows superficial perivascular inflammation with or without mild inflammation around sweat glands in the mid dermis and (iv) patients lack other associated cutaneous or internal abnormalities.

Keywords: annular erythema; erythema papulatum centrifugum; erythema papulosa semicircularis recidivans.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Erythema / etiology*
  • Erythema / pathology*
  • Erythema / therapy
  • Female
  • Humans
  • Skin Diseases, Genetic / etiology*
  • Skin Diseases, Genetic / pathology*
  • Skin Diseases, Genetic / therapy

Supplementary concepts

  • Annular Erythema