Thymoma-Induced Autoimmune Hepatitis: A Rare Paraneoplastic Syndrome

Cureus. 2019 Sep 12;11(9):e5637. doi: 10.7759/cureus.5637.

Abstract

Thymomas are rare neoplasms of the thymus and are often associated with immune-mediated paraneoplastic syndromes, most commonly, myasthenia gravis. The same underlying mechanism can produce antibodies to other self-antigens in various organ systems. Autoimmune hepatitis is a rare complication of thymoma. We present a 35-year-old healthy male, initially thought to have drug-induced liver injury, who was subsequently diagnosed with thymoma-induced autoimmune hepatitis, a rare syndrome of which only two previous cases have been reported.

Keywords: autoimmune hepatitis; autoimmunity; paraneoplastic syndrome; thymoma.

Publication types

  • Case Reports