Metal/Metal Oxide Nanoparticles: Toxicity, Applications, and Future Prospects

Curr Pharm Des. 2019;25(37):4013-4029. doi: 10.2174/1381612825666191111091326.

Abstract

The ever-growing resistance of pathogens to antibiotics and crop disease due to pest has triggered severe health concerns in recent years. Consequently, there is a need of powerful and protective materials for the eradication of diseases. Metal/metal oxide nanoparticles (M/MO NPs) are powerful agents due to their therapeutic effects in microbial infections. In this context, the present review article discusses the toxicity, fate, effects and applications of M/MO NPs. This review starts with an introduction, followed by toxicity aspects, antibacterial and testing methods and mechanism. In addition, discussion on the impact of different M/MO NPs and their characteristics such as size, shape, particle dissolution on their induced toxicity on food and plants, as well as applications in pesticides. Finally, prospective on current and future issues are presented.

Keywords: Metal oxide nanoparticles; callus poisoning; microbial assay; pest control; plant biotechnology; toxicity..

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents
  • Metal Nanoparticles / toxicity*
  • Oxides / toxicity*
  • Pesticides
  • Plants / drug effects

Substances

  • Anti-Bacterial Agents
  • Oxides
  • Pesticides