Thromboses in tuberculosis are linked to antiphosphatidylethanolamine antibodies levels: A cross-sectional study

Simon Bessis; Daniel Bertin; Matthieu Million; Line Meddeb; Michel Drancourt; Jean-Christophe Lagier; Jean-Louis Mège; Nathalie Bardin; Philippe Brouqui

doi:10.1016/j.jctube.2019.100092

Thromboses in tuberculosis are linked to antiphosphatidylethanolamine antibodies levels: A cross-sectional study

J Clin Tuberc Other Mycobact Dis. 2019 Feb 15:15:100092. doi: 10.1016/j.jctube.2019.100092. eCollection 2019 May.

Authors

Simon Bessis^{1

2}, Daniel Bertin³, Matthieu Million^{1

2}, Line Meddeb¹, Michel Drancourt^{1

2}, Jean-Christophe Lagier^{1

2}, Jean-Louis Mège³, Nathalie Bardin³, Philippe Brouqui^{1

2}

Affiliations

¹ AP-HM, IHU-Méditerranée Infection, Marseille, France.
² Aix-Marseille Univ, IRD, IHU-Méditerranée Infection, MEPHI, Marseille, France.
³ Laboratoire d'immunologie, Hôpital de la Conception, Assistance Publique Hôpitaux de Marseille, 19-21 boulevard, Jean Moulin, Marseille 13005, France.

Abstract

Venous thromboses have been associated with tuberculosis, but the relationship with circulating anticoagulant has not been studied yet. In a cohort of 48 patients with tuberculosis, 22.9% of them presented with venous thromboses significantly associated with dose dependent level of antiphosphophatidyl-ethanolamine antibodies.

Keywords: Anti-phosphatidylethanolamine antibodies; Antiphospholipds antibodies; Deep vein thrombosis; Mycobacterium tuberculosis; Pulmonary embolism; Tuberculosis.