Lack of evidence for the presence of leprosy bacilli in red squirrels from North-West Europe

Transbound Emerg Dis. 2020 Mar;67(2):1032-1034. doi: 10.1111/tbed.13423. Epub 2019 Dec 2.

Abstract

Leprosy is a human infectious disease caused by Mycobacterium leprae or Mycobacterium lepromatosis that can also occur in animals and even manifest as zoonosis. Recently, both mycobacteria were detected in red squirrels (Sciurus vulgaris) from the British Isles. To further explore the presence of leprosy bacilli in North-West Europe, we screened Belgian and Dutch squirrels. Tissue samples from 115 animals tested by qPCR were negative for both pathogens. No molecular or pathological evidence was found of the presence of these zoonotic pathogens in North-West Europe.

Keywords: Mycobacterium leprae; Mycobacterium lepromatosis; OneHealth; leprosy; red squirrel; zoonosis.

MeSH terms

  • Animals
  • Belgium / epidemiology
  • Humans
  • Leprosy / microbiology
  • Leprosy / veterinary*
  • Mycobacterium / genetics
  • Mycobacterium / isolation & purification*
  • Mycobacterium leprae / genetics
  • Mycobacterium leprae / isolation & purification*
  • Netherlands / epidemiology
  • Sciuridae / microbiology*
  • United Kingdom / epidemiology
  • Zoonoses

Supplementary concepts

  • Mycobacterium lepromatosis