Trientine-induced Rhabdomyolysis in an Adolescent with Wilson's Disease

Nagehan Aslan; Sibel Yavuz; Dincer Yildizdas; Ozden Ozgur Horoz; Yasemin Coban; Gokhan Tumgor; Aysun Karabay Bayazit

doi:10.5005/jp-journals-10071-23271

Trientine-induced Rhabdomyolysis in an Adolescent with Wilson's Disease

Indian J Crit Care Med. 2019 Oct;23(10):489-490. doi: 10.5005/jp-journals-10071-23271.

Authors

Nagehan Aslan¹, Sibel Yavuz², Dincer Yildizdas¹, Ozden Ozgur Horoz¹, Yasemin Coban¹, Gokhan Tumgor², Aysun Karabay Bayazit³

Affiliations

¹ Department of Pediatrics, Division of Pediatric Intensive Care Unit, Cukurova University, Faculty of Medicine, Adana, Turkey.
² Department of Pediatrics, Division of Pediatric Gastroenterology, Cukurova University, Faculty of Medicine, Adana, Turkey.
³ Department of Pediatrics, Division of Pediatric Nephrology, Cukurova University, Faculty of Medicine, Adana, Turkey.

Abstract

Background: Drugs are very important in the etiology of nontraumatic rhabdomyolysis.

Case descriptions: A 16-year-old male patient with Wilson's disease was admitted for myoclonic contractions. Oral trientine was started for neurological problems and tremor on the hands due to D-penicillamine 1 month ago. Patient was oligoanuric, and his creatine kinase level was 15197 U/L. Rhabdomyolysis was associated with trientine, and trientine treatment was stopped. Hemodiafiltration was performed. The patient began to urinate on the 24th day.

Conclusion: This is the first pediatric patient with rhabdomyolysis induced by trientine. Drugs used should be questioned carefully in patients with rhabdomyolysis.

How to cite this article: Aslan N, Yavuz S, Yildizdas D, Horoz OO, Coban Y, Tumgor G, et al. Trientine-induced Rhabdomyolysis in an Adolescent with Wilson's Disease. Indian J Crit Care Med 2019;23(10):489-490.

Keywords: Continued renal replacement therapy; Rhabdomyolysis; Trientine.

Publication types

Case Reports