Peste des petits ruminants viruses of lineages II and III identified in the Democratic Republic of the Congo

Georges Mbuyi Tshilenge; Julienne Sumbu Walandila; Daudet Byakya Kikukama; Justin Masumu; Louison Katshay Balowa; Giovanni Cattoli; Ezekiel Bushu; Serge Mpiana Tshipambe; William G Dundon

doi:10.1016/j.vetmic.2019.108493

Peste des petits ruminants viruses of lineages II and III identified in the Democratic Republic of the Congo

Vet Microbiol. 2019 Dec:239:108493. doi: 10.1016/j.vetmic.2019.108493. Epub 2019 Nov 4.

Authors

Georges Mbuyi Tshilenge¹, Julienne Sumbu Walandila², Daudet Byakya Kikukama², Justin Masumu³, Louison Katshay Balowa², Giovanni Cattoli⁴, Ezekiel Bushu⁵, Serge Mpiana Tshipambe², William G Dundon⁶

Affiliations

¹ Central Veterinary Laboratory, Wangata Street, P.O. Box 8842, Gombe, Kinshasa, Democratic Republic of the Congo; Faculty of Veterinary Medicine, University of Kinshasa, University Street, P.O. Box 117, Kinshasa XI, Democratic Republic of the Congo.
² Central Veterinary Laboratory, Wangata Street, P.O. Box 8842, Gombe, Kinshasa, Democratic Republic of the Congo.
³ Central Veterinary Laboratory, Wangata Street, P.O. Box 8842, Gombe, Kinshasa, Democratic Republic of the Congo; Faculty of Veterinary Medicine, National Pedagogic University, Matadi/ Liberation Street, P.O. Box 8815, Ngaliema, Kinshasa, Congo; National Institute for Biomedical Research (INRB), 5345 Democratie Street, P.O. Box 1197, Gombe, Kinshasa, Democratic Republic of the Congo.
⁴ Animal Production and Health Laboratory, Animal Production and Health Section, Joint FAO/IAEA Division, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna, Austria.
⁵ Goma Veterinary Laboratory, Goma/North-Kivu, Democratic Republic of the Congo.
⁶ Animal Production and Health Laboratory, Animal Production and Health Section, Joint FAO/IAEA Division, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna, Austria. Electronic address: [email protected].

PMID: 31767093
DOI: 10.1016/j.vetmic.2019.108493

Abstract

Understanding the molecular epidemiology and evolution of peste des petits ruminants virus (PPRV), the causative agent of Peste des petits ruminants, can assist in the control of the transboundary spread of this economically important disease. To date, despite having been reported in the majority of northern and central African countries, no molecular epidemiological data on PPRVs are available for the Democratic Republic of the Congo (DRC). This study reports the collection and analysis of 11 samples collected from three provinces of the DRC in 2016 and 2018. Sequence analysis identified two (i.e. II and III) of the four known lineages of PPRV in the country providing important information that will assist in the global eradication of PPR.

Keywords: Co-circulation; Democratic Republic of the Congo; Lineage II; Lineage III; Peste des petits ruminants; Small ruminant morbillivirus.

MeSH terms

Animals
Base Sequence
Democratic Republic of the Congo / epidemiology
Disease Eradication
Molecular Epidemiology
Peste-des-Petits-Ruminants / epidemiology
Peste-des-Petits-Ruminants / prevention & control
Peste-des-Petits-Ruminants / virology*
Peste-des-petits-ruminants virus / classification*
Peste-des-petits-ruminants virus / genetics
RNA, Viral / chemistry
RNA, Viral / genetics

Substances

RNA, Viral