Type I interferon signature predicts response to JAK inhibition in haploinsufficiency of A20

Ann Rheum Dis. 2020 Mar;79(3):429-431. doi: 10.1136/annrheumdis-2019-215918. Epub 2019 Nov 25.
No abstract available

Keywords: DMARDs (synthetic); cytokines; fever syndromes.

Publication types

  • Letter
  • Research Support, N.I.H., Intramural

MeSH terms

  • Adolescent
  • Adult
  • Female
  • Haploinsufficiency / drug effects*
  • Humans
  • Interferon Type I / metabolism*
  • Janus Kinase Inhibitors / pharmacology*
  • Loss of Function Mutation / drug effects
  • Male
  • Middle Aged
  • NF-kappa B / metabolism
  • Signal Transduction / drug effects
  • Tumor Necrosis Factor alpha-Induced Protein 3 / genetics*
  • Young Adult

Substances

  • Interferon Type I
  • Janus Kinase Inhibitors
  • NF-kappa B
  • TNFAIP3 protein, human
  • Tumor Necrosis Factor alpha-Induced Protein 3