Cost-Effectiveness of a Weight Loss Intervention: An Adaptation of the Look AHEAD Lifestyle Intervention in the US Military

Obesity (Silver Spring). 2020 Jan;28(1):89-96. doi: 10.1002/oby.22681. Epub 2019 Nov 26.

Abstract

Objective: This study aimed to assess whether a counselor-initiated (CI) adaptation of the Look AHEAD (Action for Health in Diabetes) intensive lifestyle intervention in a military setting was cost-effective relative to a self-paced (SP) adaptation.

Methods: A cost-effectiveness analysis from a payer perspective was performed alongside a 2014-2017 randomized behavioral weight loss trial among 248 active-duty military personnel stationed at a US Air Force base in Texas. Incremental cost-effectiveness ratios were calculated for weight loss, reductions in waist circumference, and quality-adjusted life-years (QALYs).

Results: After 12 months, the CI adaptation cost more per participant compared with the SP adaptation ($1,081 vs. $120) but achieved greater weight loss (1.86 kg vs. 0.06 kg), greater reductions in waist circumference (1.85 cm vs. 0.48 cm), and more QALYs (0.871 vs. 0.856). The incremental cost-effectiveness ratio for the CI adaptation relative to the SP adaptation was $61,268 per additional QALY. At willingness-to-pay thresholds of $50,000 and $100,000 per QALY, the CI adaptation was 45% and 49% likely to be cost-effective, respectively.

Conclusions: The CI delivery of the Look AHEAD Intensive Lifestyle Intervention may offer a cost-effective approach to tackle excess weight in the US military.

Trial registration: ClinicalTrials.gov NCT02063178.

Publication types

  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Cost-Benefit Analysis
  • Female
  • Humans
  • Life Style
  • Male
  • Middle Aged
  • Military Personnel* / statistics & numerical data
  • Overweight / economics*
  • Overweight / epidemiology
  • Overweight / therapy*
  • Physical Fitness / physiology
  • Quality-Adjusted Life Years
  • Texas / epidemiology
  • United States / epidemiology
  • Weight Loss / physiology
  • Weight Reduction Programs / economics*
  • Weight Reduction Programs / methods
  • Weight Reduction Programs / statistics & numerical data
  • Young Adult

Associated data

  • ClinicalTrials.gov/NCT02063178