Imbalance in T-Helper 17 Cells and Targeted Therapy in an Infant with SAM-like Syndrome

N Engl J Med. 2019 Nov 28;381(22):2176-2178. doi: 10.1056/NEJMc1908531.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Antibodies, Monoclonal, Humanized / therapeutic use*
  • Dermatitis, Exfoliative / drug therapy*
  • Dermatitis, Exfoliative / immunology
  • Failure to Thrive / drug therapy
  • Female
  • Humans
  • Hypotrichosis / drug therapy
  • Infant
  • Interleukin-17 / antagonists & inhibitors*
  • Interleukin-17 / immunology
  • Keratoderma, Palmoplantar / drug therapy*
  • Keratoderma, Palmoplantar / immunology
  • Lymphocyte Count
  • Nails, Malformed / drug therapy
  • Syndrome
  • T-Lymphocytes, Helper-Inducer / physiology*

Substances

  • Antibodies, Monoclonal, Humanized
  • IL17A protein, human
  • Interleukin-17
  • secukinumab