Late onset absolute neutropenia associated with ocrelizumab treatment in multiple sclerosis: A case report and review of the literature

J Neurol Sci. 2020 Feb 15:409:116603. doi: 10.1016/j.jns.2019.116603. Epub 2019 Nov 28.
No abstract available

Keywords: Anti-CD20; Late onset absolute neutropenia; Monoclonal antibody treatment; Multiple sclerosis; Ocrelizumab; Treatment naïve.

Publication types

  • Case Reports
  • Letter
  • Review

MeSH terms

  • Adult
  • Antibodies, Monoclonal, Humanized / adverse effects*
  • Female
  • Humans
  • Immunologic Factors / adverse effects*
  • Multiple Sclerosis, Relapsing-Remitting / blood*
  • Multiple Sclerosis, Relapsing-Remitting / drug therapy*
  • Neutropenia / blood*
  • Neutropenia / chemically induced*
  • Neutropenia / diagnosis
  • Treatment Outcome

Substances

  • Antibodies, Monoclonal, Humanized
  • Immunologic Factors
  • ocrelizumab