Multiple roles of PTEN isoforms PTENα and PTENβ in cellular activities and tumor development

Sci China Life Sci. 2019 Dec;62(12):1722-1724. doi: 10.1007/s11427-019-1595-2. Epub 2019 Dec 1.

Authors

Hui Liang¹, Yuxin Yin²

Affiliations

¹ Institute of Systems Biomedicine, Department of Pathology, School of Basic Medical Sciences, Peking-Tsinghua Center for Life Sciences, Peking University Health Science Center, Beijing, 100191, China.
² Institute of Systems Biomedicine, Department of Pathology, School of Basic Medical Sciences, Peking-Tsinghua Center for Life Sciences, Peking University Health Science Center, Beijing, 100191, China. [email protected].

PMID: 31823204
DOI: 10.1007/s11427-019-1595-2

No abstract available

Publication types

Review

MeSH terms

Animals
Gene Expression Regulation
Genes, Suppressor
Humans
Mutant Proteins / chemistry*
Mutant Proteins / genetics
Mutant Proteins / metabolism*
Neoplasms / metabolism*
PTEN Phosphohydrolase / chemistry*
PTEN Phosphohydrolase / genetics
PTEN Phosphohydrolase / metabolism*
Prognosis
Protein Conformation
Protein Isoforms
Protein Multimerization
Structure-Activity Relationship

Substances

Mutant Proteins
Protein Isoforms
PTEN Phosphohydrolase
PTEN protein, human