Cabazitaxel Induced Thrombotic Microangiopathy in a Patient with Prostate Cancer

Case Rep Nephrol. 2019 Nov 19:2019:8591283. doi: 10.1155/2019/8591283. eCollection 2019.

Abstract

Cancer-associated thrombotic microangiopathy (TMA) refers to a group of disorders characterized by microangiopathic haemolytic anemia, thrombocytopenia, and ischemic organ damage. TMA manifestations can be induced by cancer or by chemotherapy. We report the case of a 64-year-old man with metastatic prostate cancer who experienced a Cabazitaxel-induced TMA manifestation. TMA responds to conservative therapy, dialysis without plasmaphoresis, with progressive recovered renal function.

Publication types

  • Case Reports