A case of advanced prostate cancer controlled for the long term by flutamide after bicalutamide failure

Nagoya J Med Sci. 2019 Nov;81(4):707-710. doi: 10.18999/nagjms.81.4.707.

Abstract

Currently, the early introduction of new antiandrogens is popular for castration-resistant prostate cancer (CRPC). However, adverse events can be severe and their costs are high. Here, we present a patient with CRPC in whom flutamide controlled disease progression for 10 years. This case report shows that conventional alternative antiandrogens are cost effective and are still an important option for the treatment for CRPC.

Keywords: bicalutamide; flutamide; long-term; prostate cancer.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anilides / therapeutic use*
  • Disease Progression
  • Flutamide / therapeutic use*
  • Humans
  • Male
  • Nitriles / therapeutic use*
  • Prostatic Neoplasms / drug therapy*
  • Prostatic Neoplasms, Castration-Resistant / drug therapy*
  • Temperature
  • Tosyl Compounds / therapeutic use*

Substances

  • Anilides
  • Nitriles
  • Tosyl Compounds
  • Flutamide
  • bicalutamide