Renal manifestations of sarcoidosis: from accurate diagnosis to specific treatment

Int Braz J Urol. 2020 Jan-Feb;46(1):15-25. doi: 10.1590/S1677-5538.IBJU.2019.0042.

Abstract

Sarcoidosis is a multisystem granulomatous disease characterized by epithelioid noncaseating granulomas associated with clinical and radiologic findings. The cause of this disease is still uncertain. Sarcoidosis affects mostly lungs and lymph nodes and is not usually considered a urological disease, therefore, this etiology may be overlooked in several urological disorders, such as hypercalcemia, hypercalciuria and nephrolithiasis. It affects all races and genders. This review aims to describe the urological manifestations of sarcoidosis and to elucidate how the disease may affect the management of numerous urological conditions.

Keywords: Granulomatous Disease, Chronic; Sarcoidosis; therapy [Subheading].

Publication types

  • Review

MeSH terms

  • Biopsy
  • Chronic Disease
  • Humans
  • Hypercalcemia / diagnosis
  • Hypercalcemia / pathology
  • Hypercalciuria / diagnosis
  • Hypercalciuria / pathology
  • Kidney Diseases / diagnosis
  • Kidney Diseases / pathology*
  • Kidney Diseases / therapy
  • Sarcoidosis / diagnosis
  • Sarcoidosis / pathology*
  • Sarcoidosis / therapy