Herpes Simplex virus type 2 myeloradiculitis with a pure motor presentation in a liver transplant recipient

Transpl Infect Dis. 2020 Feb;22(1):e13236. doi: 10.1111/tid.13236. Epub 2020 Jan 1.

Abstract

In this case report, we describe the first PCR-confirmed case of HSV2 myeloradiculitis with a purely motor presentation, occurring in a 68-year-old liver transplant recipient. The patient reported ascending weakness with no sensory nor sphincteric symptoms, thereby resembling acute demyelinating inflammatory neuropathy, or Guillain-Barré syndrome. HSV2 was detected in cerebrospinal fluid by PCR, and the patient was successfully treated with intravenous Acyclovir.

Keywords: Elsberg syndrome; HSV2 infection; Herpes simplex virus type 2; ascending weakness; liver transplant; myeloradiculitis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Acyclovir / therapeutic use
  • Aged
  • Antiviral Agents / therapeutic use
  • Guillain-Barre Syndrome / virology*
  • Herpes Simplex / cerebrospinal fluid*
  • Herpes Simplex / drug therapy
  • Herpesvirus 2, Human
  • Humans
  • Liver Transplantation / adverse effects*
  • Male
  • Treatment Outcome

Substances

  • Antiviral Agents
  • Acyclovir