Verruciform xanthoma in a patient with recessive dystrophic epidermolysis bullosa: Case report and literature review

Pediatr Dermatol. 2020 Mar;37(2):355-357. doi: 10.1111/pde.14079. Epub 2019 Dec 26.

Abstract

Verruciform xanthoma (VX) is a rare finding thought to be caused by epidermal damage from trauma or inflammation and has been reported in a limited number of patients with recessive dystrophic epidermolysis bullosa (RDEB). Herein, we describe a 20-year-old woman with RDEB who developed a large, verrucous, pink plaque on the posterior thigh that was histologically proven to be a VX. We review cases of VX in patients with RDEB and summarize the clinical features, pathophysiology, and management principles.

Keywords: epidermolysis bullosa; neoplasms- benign.

Publication types

  • Case Reports

MeSH terms

  • Epidermolysis Bullosa Dystrophica / complications*
  • Epidermolysis Bullosa Dystrophica / pathology*
  • Female
  • Humans
  • Xanthomatosis / etiology*
  • Xanthomatosis / pathology*
  • Young Adult